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Synergistic Combination Chemotherapy of Lung Cancer: Cisplatin and Doxorubicin Conjugated Prodrug Loaded, Glutathione and pH Sensitive Nanocarriers

PURPOSE: Prodrug technology-based combination drug therapy has been exploited as a promising treatment strategy to achieve synergistic lung cancer therapy, reduce drug dose, and decrease side effects. In the present study, we synthesized a pH and glutathione (GSH) sensitive prodrug, cisplatin (CIS)...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Jin, Yonglong, Wang, Yi, Liu, Xiguang, Zhou, Jing, Wang, Xintong, Feng, Hui, Liu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701144/
https://ncbi.nlm.nih.gov/pubmed/33268983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S260253
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