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Purification of a heterodimeric Reelin construct to investigate binding stoichiometry
Reelin is a secreted glycoprotein that is integral in neocortex development and synaptic function. Reelin exists as a homodimer with two chains linked by a disulfide bond at cysteine 2101, a feature that is vital to the protein’s function. This is highlighted by the fact that only dimeric Reelin can...
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| Publicado no: | Eur Biophys J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7701066/ https://ncbi.nlm.nih.gov/pubmed/33057791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-020-01465-6 |
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