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Data Mining for Adverse Events of Tumor Necrosis Factor-Alpha Inhibitors in Pediatric Patients: Tree-Based Scan Statistic Analyses of Danish Nationwide Health Data

BACKGROUND AND OBJECTIVES: Tumor necrosis factor-alpha (TNF-α) inhibitors are efficacious and considered generally safe in adults. However, pediatric-specific safety evidence is scarce. The aim of this study was to screen for signals of previously unknown adverse events of TNF-α inhibitors in pediat...

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Détails bibliographiques
Publié dans:Clin Drug Investig
Auteurs principaux: Wintzell, Viktor, Svanström, Henrik, Melbye, Mads, Ludvigsson, Jonas F., Pasternak, Björn, Kulldorff, Martin
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701063/
https://ncbi.nlm.nih.gov/pubmed/33104987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-020-00977-5
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