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A Multi-Objective Approach for Anti-Osteosarcoma Cancer Agents Discovery through Drug Repurposing

Osteosarcoma is the most common type of primary malignant bone tumor. Although nowadays 5-year survival rates can reach up to 60–70%, acute complications and late effects of osteosarcoma therapy are two of the limiting factors in treatments. We developed a multi-objective algorithm for the repurposi...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Cabrera-Andrade, Alejandro, López-Cortés, Andrés, Jaramillo-Koupermann, Gabriela, González-Díaz, Humberto, Pazos, Alejandro, Munteanu, Cristian R., Pérez-Castillo, Yunierkis, Tejera, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700154/
https://ncbi.nlm.nih.gov/pubmed/33266378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13110409
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