Berberine Inhibits Cell Proliferation by Interfering with Wild-Type and Mutant P53 in Human Glioma Cells

INTRODUCTION: Glioma is the most common malignant brain tumor. TP53 is the most common mutant gene in human cancer. Wild-type p53 (wtp53) is a tumor suppressor protein whereas mutant p53 (mutp53) is an oncoprotein that promotes tumor cell proliferation. Our aim was to examine the inhibitory effects...

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Bibliografske podrobnosti
izdano v:Onco Targets Ther
Main Authors: Liu, Ziqiang, Chen, Yong, Gao, Haijun, Xu, Weidong, Zhang, Chaochao, Lai, Jiacheng, Liu, Xingxing, Sun, Yuxue, Huang, Haiyan
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699991/
https://ncbi.nlm.nih.gov/pubmed/33262612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S279002
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