Isotope Fractionation during Gas Chromatography Can Enhance Mass Spectrometry-Based Measures of (2)H-Labeling of Small Molecules

Stable isotope tracers can be used to quantify the activity of metabolic pathways. Specifically, (2)H-water is quite versatile, and its incorporation into various products can enable measurements of carbohydrate, lipid, protein and nucleic acid kinetics. However, since there are limits on how much (...

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Bibliografske podrobnosti
izdano v:Metabolites
Main Authors: Downes, Daniel P., Kasumov, Takhar, Daurio, Natalie A., Wood, Neil B., Previs, Michael J., Sheth, Payal R., McLaren, David G., Previs, Stephen F.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699861/
https://ncbi.nlm.nih.gov/pubmed/33233825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo10110474
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