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Liraglutide Activates Glucagon-Like Peptide 1 Receptor to Attenuate Hyperglycemia through Endogenous Beta-Endorphin in Diabetic Rats

Liraglutide, an acylated analog of glucagon-like peptide 1 (GLP-1), could improve glycemic control in diabetes. Moreover, endogenous opioid peptides play a role in blood sugar regulation. Since GLP-1 receptors are also expressed in extra-pancreatic tissues, this study investigates the effect of lira...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Cheng, Kai-Chun, Li, Ying-Xiao, Shieh, Po-Chuen, Cheng, Juei-Tang, Hsu, Chia-Chen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699724/
https://ncbi.nlm.nih.gov/pubmed/33233692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13110407
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