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Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy

Loss of muscle tone triggered by emotions is called cataplexy and is the pathognomonic symptom of narcolepsy, which is caused by hypocretin deficiency. Cataplexy is classically considered to be an abnormal manifestation of REM sleep and is treated by selective serotonin (5HT) reuptake inhibitors. He...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Seifinejad, Ali, Li, Sha, Possovre, Marie-Laure, Vassalli, Anne, Tafti, Mehdi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699625/
https://ncbi.nlm.nih.gov/pubmed/33247179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19862-y
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