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Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy

Loss of muscle tone triggered by emotions is called cataplexy and is the pathognomonic symptom of narcolepsy, which is caused by hypocretin deficiency. Cataplexy is classically considered to be an abnormal manifestation of REM sleep and is treated by selective serotonin (5HT) reuptake inhibitors. He...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Seifinejad, Ali, Li, Sha, Possovre, Marie-Laure, Vassalli, Anne, Tafti, Mehdi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699625/
https://ncbi.nlm.nih.gov/pubmed/33247179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19862-y
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