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Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy

Loss of muscle tone triggered by emotions is called cataplexy and is the pathognomonic symptom of narcolepsy, which is caused by hypocretin deficiency. Cataplexy is classically considered to be an abnormal manifestation of REM sleep and is treated by selective serotonin (5HT) reuptake inhibitors. He...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Seifinejad, Ali, Li, Sha, Possovre, Marie-Laure, Vassalli, Anne, Tafti, Mehdi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699625/
https://ncbi.nlm.nih.gov/pubmed/33247179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19862-y
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