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Toward the Identification of Novel Antimicrobial Agents: One-Pot Synthesis of Lipophilic Conjugates of N-Alkyl d- and l-Iminosugars

In the effort to improve the antimicrobial activity of iminosugars, we report the synthesis of lipophilic iminosugars 10a–b and 11a–b based on the one-pot conjugation of both enantiomeric forms of N-butyldeoxynojirimycin (NBDNJ) and N-nonyloxypentyldeoxynojirimycin (NPDNJ) with cholesterol and a suc...

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Publicat a:Mar Drugs
Autors principals: Esposito, Anna, D’Alonzo, Daniele, D’Errico, Stefano, De Gregorio, Eliana, Guaragna, Annalisa
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699595/
https://ncbi.nlm.nih.gov/pubmed/33228211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18110572
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