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Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects

PURPOSE: Evogliptin, a dipeptidyl peptidase-4 inhibitor, and glimepiride, a sulfonylurea, are used to treat type 2 diabetes mellitus. In this study, we aimed to evaluate the pharmacokinetic (PK) and pharmacodynamic (PD) interactions between evogliptin and glimepiride. MATERIALS AND METHODS: A random...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Des Devel Ther
Prif Awduron: Yoo, Hyounggyoon, Kim, Yun, Jang, In-Jin, Yu, Kyung-Sang, Lee, SeungHwan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699451/
https://ncbi.nlm.nih.gov/pubmed/33262578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S275343
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