Mini-Review on Lipofuscin and Aging: Focusing on The Molecular Interface, The Biological Recycling Mechanism, Oxidative Stress, and The Gut-Brain Axis Functionality

Intra-lysosomal accumulation of the autofluorescent “residue” known as lipofuscin, which is found within postmitotic cells, remains controversial. Although it was considered a harmless hallmark of aging, its presence is detrimental as it continually accumulates. The latest evidence highlighted that...

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Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Medicina (Kaunas)
Hauptverfasser: Ilie, Ovidiu-Dumitru, Ciobica, Alin, Riga, Sorin, Dhunna, Nitasha, McKenna, Jack, Mavroudis, Ioannis, Doroftei, Bogdan, Ciobanu, Adela-Magdalena, Riga, Dan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699382/
https://ncbi.nlm.nih.gov/pubmed/33228124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina56110626
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