Macrophage Polarization in Chronic Lymphocytic Leukemia: Nurse-Like Cells Are the Caretakers of Leukemic Cells

Macrophages are terminally differentiated innate immune cells. Through their activation, they can be polarized towards the pro-inflammatory M1 type or the wound healing-associated, anti-inflammatory M2 type macrophages. In the tumor microenvironment (TME), M2 is the dominant phenotype and these cell...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Mesaros, Oana, Jimbu, Laura, Neaga, Alexandra, Popescu, Cristian, Berceanu, Iulia, Tomuleasa, Ciprian, Fetica, Bogdan, Zdrenghea, Mihnea
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699370/
https://ncbi.nlm.nih.gov/pubmed/33228048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8110516
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