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The Role of Structure and Biophysical Properties in the Pleiotropic Effects of Statins
Statins are a class of drugs used to lower low-density lipoprotein cholesterol and are amongst the most prescribed medications worldwide. Most statins work as a competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGR), but statin intolerance from pleiotropic effects have been...
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| Published in: | Int J Mol Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7699354/ https://ncbi.nlm.nih.gov/pubmed/33228116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228745 |
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