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SPDR-01 Paired epithelioid glioblastoma patient-derived xenograft models to evaluate resistant mechanism for molecular target therapy
Epithelioid glioblastoma (E-GBM) arises at younger age, commonly disseminates to cerebrospinal fluid, and results in dismal prognosis. About half of E-GBM harbors BRAF V600E mutation, thus BRAF/MEK inhibitors are expected to be specifically sensitive to E-GBM like other BRAF V600E mutant carcinomas....
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發表在: | Neurooncol Adv |
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Main Authors: | , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Oxford University Press
2020
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7699076/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa143.020 |
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