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ML-14 Re-challenge and maintenance therapy of methotrexate for elderly PCNSL patients with low scored KPS

Purpose: The delayed neuronal toxicity after high dose methotrexate (HD-MTX) followed by radiotherapy (RT) is a serious problem for elderly primary CNS lymphoma patients. We started maintenance therapy (MT) with MTX after achieving complete remission (CR) to defer RT for elderly and poor Karnofsky P...

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Publicado en:Neurooncol Adv
Autores principales: Yamaguchi, Takashi, Nagayama, Rie, Gomi, Akira, Kawai, Kensuke
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699049/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa143.074
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