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Impact of A134 and E218 Amino Acid Residues of Tropomyosin on Its Flexibility and Function

Tropomyosin (Tpm) is one of the major actin-binding proteins that play a crucial role in the regulation of muscle contraction. The flexibility of the Tpm molecule is believed to be vital for its functioning, although its role and significance are under discussion. We choose two sites of the Tpm mole...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Marchenko, Marina A., Nefedova, Victoria V., Yampolskaya, Daria S., Kopylova, Galina V., Shchepkin, Daniil V., Bershitsky, Sergey Y., Koubassova, Natalia A., Tsaturyan, Andrey K., Levitsky, Dmitrii I., Matyushenko, Alexander M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698929/
https://ncbi.nlm.nih.gov/pubmed/33218166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228720
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