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The Molecular and Functional Characteristics of HLA-G and the Interaction with Its Receptors: Where to Intervene for Cancer Immunotherapy?

Human leukocyte antigen G (HLA-G) mediates maternal-fetal immune tolerance. It is also considered an immune checkpoint in cancer since it may mediate immune evasion and thus promote tumor growth. HLA-G is, therefore, a potential target for immunotherapy. However, existing monoclonal antibodies direc...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Attia, Jiji V. D., Dessens, Charlotte E., van de Water, Ricky, Houvast, Ruben D., Kuppen, Peter J. K., Krijgsman, Daniëlle
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698525/
https://ncbi.nlm.nih.gov/pubmed/33213057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228678
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