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Transthyretin Stabilization: An Emerging Strategy for the Treatment of Alzheimer’s Disease?

Transthyretin (TTR), previously named prealbumin is a plasma protein secreted mainly by the liver and choroid plexus (CP) that is a carrier for thyroid hormones (THs) and retinol (vitamin A). The structure of TTR, with four monomers rich in β-chains in a globular tetrameric protein, accounts for the...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Saponaro, Federica, Kim, Jin Hae, Chiellini, Grazia
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698513/
https://ncbi.nlm.nih.gov/pubmed/33212973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228672
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