Segregation Analysis of Rare NRP1 and NRP2 Variants in Families with Lymphedema

Neuropilins are transmembrane coreceptors expressed by endothelial cells and neurons. NRP1 and NRP2 bind a variety of ligands, by which they trigger cell signaling, and are important in the development of lymphatic valves and lymphatic capillaries, respectively. This study focuses on identifying rar...

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Pubblicato in:Genes (Basel)
Autori principali: Michelini, Sandro, Amato, Bruno, Ricci, Maurizio, Kenanoglu, Sercan, Veselenyiova, Dominika, Kurti, Danjela, Baglivo, Mirko, Manara, Elena, Dundar, Munis, Krajcovic, Juraj, Basha, Syed Hussain, Priya, Sasi, Serrani, Roberta, Miggiano, Giacinto A. D., Aquilanti, Barbara, Matera, Giuseppina, Velluti, Valeria, Gagliardi, Lucilla, Dautaj, Astrit, Bertelli, Matteo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698471/
https://ncbi.nlm.nih.gov/pubmed/33212964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11111361
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