Neuroprotective Effect of Tricyclic Pyridine Alkaloids from Fusarium lateritium SSF2, against Glutamate-Induced Oxidative Stress and Apoptosis in the HT22 Hippocampal Neuronal Cell Line

Excessive glutamate damages neuronal cells via the accumulation of intracellular reactive oxygen species (ROS), calcium ion (Ca(2+)) influx, depolarization of mitochondrial membrane potential, and apoptosis, which may result in the development of chronic neurodegenerative diseases. In this study, we...

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Publicado en:Antioxidants (Basel)
Main Authors: Lee, Dahae, Choi, Hyun Gyu, Hwang, Ji Hye, Shim, Sang Hee, Kang, Ki Sung
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698086/
https://ncbi.nlm.nih.gov/pubmed/33187346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9111115
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