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Methods and Applications of In Silico Aptamer Design and Modeling

Aptamers are nucleic acid analogues of antibodies with high affinity to different targets, such as cells, viruses, proteins, inorganic materials, and coenzymes. Empirical approaches allow the design of in vitro aptamers that bind particularly to a target molecule with high affinity and selectivity....

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Buglak, Andrey A., Samokhvalov, Alexey V., Zherdev, Anatoly V., Dzantiev, Boris B.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698023/
https://ncbi.nlm.nih.gov/pubmed/33182550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228420
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