A “Lymphocyte MicroRNA Signature” as Predictive Biomarker of Immunotherapy Response and Plasma PD-1/PD-L1 Expression Levels in Patients with Metastatic Renal Cell Carcinoma: Pointing towards Epigenetic Reprogramming

SIMPLE SUMMARY: MicroRNAs are small molecules of non-coding RNAs which regulate gene expression at the post-transcriptional level. Normal miRNA expression and function can be deregulated in cancer. The comprehensive molecular characterization of Renal Cell Carcinoma shows several genes silenced and...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Incorvaia, Lorena, Fanale, Daniele, Badalamenti, Giuseppe, Brando, Chiara, Bono, Marco, De Luca, Ida, Algeri, Laura, Bonasera, Annalisa, Corsini, Lidia Rita, Scurria, Salvatore, Iovanna, Juan Lucio, Russo, Antonio, Bazan, Viviana
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697734/
https://ncbi.nlm.nih.gov/pubmed/33207823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113396
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