Beyond LKB1 Mutations in Non-Small Cell Lung Cancer: Defining LKB1less Phenotype to Optimize Patient Selection and Treatment

LKB1 is frequently mutated in non-small cell lung cancer (NSCLC). LKB1-mutated NSCLCs often have a dismal prognosis and receive lower benefit from the currently available therapies. LKB1 acts as a cell emergency brake in low-energy conditions, by modulating the activity of crucial anabolic enzymes....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Borzi, Cristina, Galli, Giulia, Ganzinelli, Monica, Signorelli, Diego, Vernieri, Claudio, Garassino, Marina Chiara, Sozzi, Gabriella, Moro, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697441/
https://ncbi.nlm.nih.gov/pubmed/33202760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13110385
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados