Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8(+) T Cells in Non-Melanoma Cancers Compared to Melanoma

SIMPLE SUMMARY: Human tumors are often infiltrated by T cells; however, it remains unclear what proportion of T cells infiltrating tumors are bystander and non-tumor specific. We have investigated qualitative characteristics of these tumor-infiltrating lymphocytes (TILs) based on their gene-expressi...

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Publicado en:Cancers (Basel)
Main Authors: Gokuldass, Aishwarya, Draghi, Arianna, Papp, Krisztian, Borch, Troels Holz, Nielsen, Morten, Westergaard, Marie Christine Wulff, Andersen, Rikke, Schina, Aimilia, Bol, Kalijn Fredrike, Chamberlain, Christopher Aled, Presti, Mario, Met, Özcan, Harbst, Katja, Lauss, Martin, Soraggi, Samuele, Csabai, Istvan, Szállási, Zoltán, Jönsson, Göran, Svane, Inge Marie, Donia, Marco
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696049/
https://ncbi.nlm.nih.gov/pubmed/33198174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113344
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