Gamma-oryzanol as a potential modulator of oxidative stress and inflammation via PPAR-y in adipose tissue: a hypothetical therapeutic for cytokine storm in COVID-19?

The literature has reported a higher prevalence of negative clinical outcomes due to Coronavirus disease 19 (COVID-19) in obese individuals. This can be explained by the cytokine storm, result from the cytokine production from both obesity and viral infection. Gamma-oryzanol (γOz) is a compound with...

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Pubblicato in:Mol Cell Endocrinol
Autori principali: Francisqueti-Ferron, Fabiane Valentini, Garcia, Jéssica Leite, Ferron, Artur Junio Togneri, Nakandakare- Maia, Erika Tiemi, Gregolin, Cristina Schmitt, Silva, Janaina Paixão das Chagas, dos Santos, Klinsmann Carolo, Lo, Ângelo Thompson Colombo, Siqueira, Juliana Silva, de Mattei, Letícia, de Paula, Bruno Henrique, Sarzi, Felipe, Silva, Carol Cristina Vágula de Almeida, Moreto, Fernando, Costa, Mariane Róvero, Ferreira, Ana Lucia A., Minatel, Igor Otávio, Corrêa, Camila Renata
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier B.V. 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695949/
https://ncbi.nlm.nih.gov/pubmed/33253762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2020.111095
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