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Breakdown of T-cell ignorance: The tolerance failure responsible for mainstream autoimmune diseases?

This article explores the possibility that the major autoimmune diseases come about because of the breakdown of T lymphocyte ignorance – that state in which antigen and lymphocyte have never come together in such a way as to induce tolerance or an immune response. By use of transgenic technique to p...

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Detalhes bibliográficos
Publicado no:J Transl Autoimmun
Main Authors: Salaman, Myer R., Gould, Keith G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695872/
https://ncbi.nlm.nih.gov/pubmed/33294833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtauto.2020.100070
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