Chitosan-Coated Hydroxypropylmethyl Cellulose Microparticles of Levodopa (and Carbidopa): In Vitro and Rat Model Kinetic Characteristics

BACKGROUND: Parkinson's disease is a neurodegenerative disorder, and a major cause of disability. Levodopa, a prodrug of dopamine, remains the gold standard in the pharmacological management of Parkinson's disease. Despite several attempts to improve the clinical efficacy of levodopa, new...

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Publicat a:Curr Ther Res Clin Exp
Autors principals: Dankyi, Benedicta Obenewaa, Amponsah, Seth Kwabena, Allotey-Babington, Grace Lovia, Adams, Ismaila, Goode, Nana Aboadwe, Nettey, Henry
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695871/
https://ncbi.nlm.nih.gov/pubmed/33296447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2020.100612
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