Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence

Senescence is a state of stable proliferative arrest, generally accompanied by the senescence-associated secretory phenotype, which modulates tissue homeostasis. Enhancer-promoter interactions, facilitated by chromatin loops, play a key role in gene regulation but their relevance in senescence remai...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Olan, Ioana, Parry, Aled J., Schoenfelder, Stefan, Narita, Masako, Ito, Yoko, Chan, Adelyne S. L., Slater, Guy St.C., Bihary, Dóra, Bando, Masashige, Shirahige, Katsuhiko, Kimura, Hiroshi, Samarajiwa, Shamith A., Fraser, Peter, Narita, Masashi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695716/
https://ncbi.nlm.nih.gov/pubmed/33247104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19878-4
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