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β-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo

Coordinated directional migration of cells in the mesoderm layer of the early embryo is essential for organization of the body plan. Here we show that mesoderm organization in mouse embryos depends on β-Pix (Arhgef7), a guanine nucleotide exchange factor for Rac1 and Cdc42. As early as E7.5, β-Pix m...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Omelchenko, Tatiana, Hall, Alan, Anderson, Kathryn V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695707/
https://ncbi.nlm.nih.gov/pubmed/33247143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19889-1
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