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Serotonergic projections to the orbitofrontal and medial prefrontal cortices differentially modulate waiting for future rewards

Optogenetic activation of serotonergic neurons in the dorsal raphe nucleus (DRN) enhances patience when waiting for future rewards, and this effect is maximized by both high probability and high timing uncertainty of reward. Here, we explored which serotonin projection areas contribute to these effe...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Miyazaki, Katsuhiko, Miyazaki, Kayoko W., Sivori, Gaston, Yamanaka, Akihiro, Tanaka, Kenji F., Doya, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695476/
https://ncbi.nlm.nih.gov/pubmed/33246957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc7246
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