Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-κB signaling pathways

In this study, we investigated the mechanisms by which puerarin alleviates osteoclast-related loss of bone mass in ovariectomy (OVX)-induced osteoporosis model mice. Puerarin-treated OVX mice exhibited higher bone density, fewer tartrate-resistant acid phosphatase (TRAcP)-positive osteoclasts, and l...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Main Authors: Xiao, Long, Zhong, Mengdan, Huang, Yu, Zhu, Jie, Tang, Wenkai, Li, Danyong, Shi, Jiandong, Lu, Aiqing, Yang, Huilin, Geng, Dechun, Li, Hong, Wang, Zhirong
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals 2020
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695364/
https://ncbi.nlm.nih.gov/pubmed/33176281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103976
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