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A surfactant-stripped cabazitaxel micelle formulation optimized with accelerated storage stability

Pluronic (Poloxomer) micelles can solubilize cabazitaxel (CTX), a second generation taxane, and then be subjected to low-temperature “surfactant-stripping” to selectively remove loose and free surfactant, thereby increasing the drug-to-surfactant ratio. We previously found that addition of certain o...

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Detalhes bibliográficos
Publicado no:Pharm Dev Technol
Main Authors: Sun, Boyang, Huang, Jing, Mabrouk, Moustafa T., Zhang, Yumiao, Jin, Honglin, Lovell, Jonathan F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695035/
https://ncbi.nlm.nih.gov/pubmed/32892678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10837450.2020.1818780
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