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Osteogenesis Imperfecta: An Update on Clinical Features and Therapies

Osteogenesis imperfecta (OI) is an inherited skeletal dysplasia characterized by bone fragility and skeletal deformities. While the majority of cases are associated with pathogenic variants in COL1A1 and COL1A2, the genes encoding type I collagen, up to 25% of cases are associated with other genes t...

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Detalhes bibliográficos
Publicado no:Eur J Endocrinol
Main Authors: Marom, Ronit, Rabenhorst, Brien M., Morello, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694877/
https://ncbi.nlm.nih.gov/pubmed/32621590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-20-0299
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