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Alagille Syndrome: Diagnostic Challenges and Advances in Management

Alagille syndrome (ALGS) is a multisystem disease characterized by cholestasis and bile duct paucity on liver biopsy in addition to variable involvement of the heart, eyes, skeleton, face, kidneys, and vasculature. The identification of JAG1 and NOTCH2 as disease-causing genes has deepened our under...

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Publicado en:Diagnostics (Basel)
Main Authors: Ayoub, Mohammed D., Kamath, Binita M.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694636/
https://ncbi.nlm.nih.gov/pubmed/33172025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics10110907
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