The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy

SIMPLE SUMMARY: Natural killer cells are innate cytotoxic lymphocytes that play a key role in the anti-tumor immune response. In the tumor microenvironment, however, the effector functions of these cells are often impaired by the induction of inhibitory surface molecules, including PD-1. In the pres...

Full description

Saved in:
Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Quatrini, Linda, Mariotti, Francesca Romana, Munari, Enrico, Tumino, Nicola, Vacca, Paola, Moretta, Lorenzo
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694632/
https://ncbi.nlm.nih.gov/pubmed/33172030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113285
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items