Reconsideration of the Semaphorin-3A Binding Motif Found in Chondroitin Sulfate Using Galnac4s-6st-Knockout Mice

The chondroitin sulfate (CS)-rich dense extracellular matrix surrounding neuron cell bodies and proximal dendrites in a mesh-like structure is called a perineuronal net (PNN). CS chains in PNNs control neuronal plasticity by binding to PNN effectors, semaphorin-3A (Sema3A) and orthodenticle homeobox...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Nadanaka, Satomi, Miyata, Shinji, Yaqiang, Bai, Tamura, Jun-ichi, Habuchi, Osami, Kitagawa, Hiroshi
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694144/
https://ncbi.nlm.nih.gov/pubmed/33143303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10111499
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