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Anti-Inflammatory Activity of a Cyclic Tetrapeptide in Mouse and Human Experimental Models

A cyclic tetrapeptide Pro-Pro-Pheβ(3)ho-Phe (4B8M) was tested for immunosuppressive activity and potential therapeutic utility in several in vitro and in vivo mouse and human models. The tetrapeptide was less toxic for mouse splenocytes in comparison to cyclosporine A (CsA) and a parent cyclolinopep...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Zimecki, Michał, Artym, Jolanta, Kałas, Wojciech, Strządała, Leon, Kaleta-Kuratewicz, Katarzyna, Kuryszko, Jan, Kaszuba, Andrzej, Kaczmarek, Krzysztof, Zabrocki, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693979/
https://ncbi.nlm.nih.gov/pubmed/33126725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12111030
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