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Indoxyl Sulfate, a Tubular Toxin, Contributes to the Development of Chronic Kidney Disease
Indoxyl sulfate (IS), a uremic toxin, causes chronic kidney disease (CKD) progression via its tubulotoxicity. After cellular uptake, IS directly induces apoptotic and necrotic cell death of tubular cells. Additionally, IS increases oxidative stress and decreases antioxidant capacity, which are assoc...
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| Publicado no: | Toxins (Basel) |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7693919/ https://ncbi.nlm.nih.gov/pubmed/33138205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12110684 |
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