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Investigation of Genetic Modifiers of Copper Toxicosis in Labrador Retrievers

Copper toxicosis is a complex genetic disorder in Labrador retrievers characterized by hepatic copper accumulation eventually leading to liver cirrhosis. The variation of hepatic copper levels in Labrador retrievers has been partly explained by mutations in ATP7A c.980C>T and ATP7B c.4358G>A....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Life (Basel)
Prif Awduron: Wu, Xiaoyan, den Boer, Elise R., Vos-Loohuis, Manon, van Steenbeek, Frank G., Monroe, Glen R., Nijman, Isaäc J., Leegwater, Peter. A. J., Fieten, Hille
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693796/
https://ncbi.nlm.nih.gov/pubmed/33142854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life10110266
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