Maternal High Fat Diet Programs Male Mice Offspring Hyperphagia and Obesity: Mechanism of Increased Appetite Neurons via Altered Neurogenic Factors and Nutrient Sensor AMPK

Maternal high-fat (HF) is associated with offspring hyperphagia and obesity. We hypothesized that maternal HF alters fetal neuroprogenitor cell (NPC) and hypothalamic arcuate nucleus (ARC) development with preferential differentiation of neurons towards orexigenic (NPY/AgRP) versus anorexigenic (POM...

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Bibliographic Details
Published in:Nutrients
Main Authors: Desai, Mina, Ferrini, Monica G., Han, Guang, Narwani, Kavita, Ross, Michael G.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693487/
https://ncbi.nlm.nih.gov/pubmed/33138074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12113326
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