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Identification of Novel Mutations and Expressions of EPAS1 in Phaeochromocytomas and Paragangliomas

Endothelial PAS domain-containing protein 1 (EPAS1) is an oxygen-sensitive component of the hypoxia-inducible factors (HIFs) having reported implications in many cancers by inducing a pseudo-hypoxic microenvironment. However, the molecular dysregulation and clinical significance of EPAS1 has never b...

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Dettagli Bibliografici
Pubblicato in:Genes (Basel)
Autori principali: Islam, Farhadul, Pillai, Suja, Gopalan, Vinod, Lam, Alfred King-Yin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693385/
https://ncbi.nlm.nih.gov/pubmed/33114456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11111254
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