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Identification of Novel Mutations and Expressions of EPAS1 in Phaeochromocytomas and Paragangliomas

Endothelial PAS domain-containing protein 1 (EPAS1) is an oxygen-sensitive component of the hypoxia-inducible factors (HIFs) having reported implications in many cancers by inducing a pseudo-hypoxic microenvironment. However, the molecular dysregulation and clinical significance of EPAS1 has never b...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Islam, Farhadul, Pillai, Suja, Gopalan, Vinod, Lam, Alfred King-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693385/
https://ncbi.nlm.nih.gov/pubmed/33114456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11111254
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