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Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics
PDA is a major cause of US cancer-related deaths. Oncogenic Kras presents in 90% of human PDAs. Kras mutations occur early in pre-neoplastic lesions but are insufficient to cause PDA. Other contributing factors early in disease progression include chronic pancreatitis, alterations in epigenetic regu...
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| Published in: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7693321/ https://ncbi.nlm.nih.gov/pubmed/33244070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77373-8 |
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