Unrestricted Feed Intake Induces β-Cell Death and Impairs Insulin Secretion in Broiler Breeder Hens

SIMPLE SUMMARY: Ad-feed intake caused transient hyperinsulinemia, but ultimately impaired insulin secretion and glucose clearance leading to hyperglycemia in broiler breeder hens. The impairments were operated at insulin gene expression and at pyruvate anaplerosis for ATP supply for insulin release....

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Bibliographic Details
Published in:Animals (Basel)
Main Authors: Huang, Yu-Feng, Chang, Ling-Chu, Chen, Chung-Yu, Chen, Yu-Hui, Walzem, Rosemary L., Chen, Shuen-Ei
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693285/
https://ncbi.nlm.nih.gov/pubmed/33114772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ani10111969
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