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Unrestricted Feed Intake Induces β-Cell Death and Impairs Insulin Secretion in Broiler Breeder Hens

SIMPLE SUMMARY: Ad-feed intake caused transient hyperinsulinemia, but ultimately impaired insulin secretion and glucose clearance leading to hyperglycemia in broiler breeder hens. The impairments were operated at insulin gene expression and at pyruvate anaplerosis for ATP supply for insulin release....

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Détails bibliographiques
Publié dans:Animals (Basel)
Auteurs principaux: Huang, Yu-Feng, Chang, Ling-Chu, Chen, Chung-Yu, Chen, Yu-Hui, Walzem, Rosemary L., Chen, Shuen-Ei
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693285/
https://ncbi.nlm.nih.gov/pubmed/33114772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ani10111969
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