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Antagonistic effects of activin A and TNF-α on the activation of L929 fibroblast cells via Smad3-independent signaling

Fibroblasts play an important role in inflammation and tissue fibrosis. Both activin A and TNF-α can activate immune cells, however, the roles and relationship of them in activating fibroblasts in inflammation remain unclear. Here, this study revealed that TNF-α promoted the release of NO and IL-6 b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jiang, Lingling, Liu, Boyang, Qi, Yan, Zhu, Linru, Cui, Xueling, Liu, Zhonghui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693280/
https://ncbi.nlm.nih.gov/pubmed/33244088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77783-8
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