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Metformin inhibits epithelial-mesenchymal transition of oral squamous cell carcinoma via the mTOR/HIF-1α/PKM2/STAT3 pathway

Epithelial-mesenchymal transition (EMT) serves an important role in the formation and development of various types of cancer, including oral squamous cell carcinoma (OSCC). Metformin, used for treating type 2 diabetes, has been revealed to exert an anticancer effect in various types of cancer, inclu...

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Опубликовано в: :Oncol Lett
Главные авторы: Yin, Weihuang, Liu, Yang, Liu, Xinchen, Ma, Xiaozhou, Sun, Bin, Yu, Ziying
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693125/
https://ncbi.nlm.nih.gov/pubmed/33262823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12292
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