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The malate–aspartate shuttle (Borst cycle): How it started and developed into a major metabolic pathway

This article presents a personal and critical review of the history of the malate–aspartate shuttle (MAS), starting in 1962 and ending in 2020. The MAS was initially proposed as a route for the oxidation of cytosolic NADH by the mitochondria in Ehrlich ascites cell tumor lacking other routes, and to...

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Detalhes bibliográficos
Publicado no:IUBMB Life
Autor principal: Borst, Piet
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693074/
https://ncbi.nlm.nih.gov/pubmed/32916028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.2367
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