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Tissue‐specific deletion of mouse basolateral uniporter LAT4 (Slc43a2) reveals its crucial role in small intestine and kidney amino acid transport

KEY POINTS: LAT4 is a broadly expressed uniporter selective for essential branched chain amino acids, methionine and phenylalanine, which are involved in epithelial transport. Its global deletion leads to an early malnutrition‐like phenotype and death within 10 days after birth. Here, we tested the...

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Bibliographische Detailangaben
Veröffentlicht in:J Physiol
Hauptverfasser: Rajendran, Anuradha, Poncet, Nadège, Oparija‐Rogenmozere, Lalita, Herzog, Brigitte, Verrey, François
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693055/
https://ncbi.nlm.nih.gov/pubmed/32841365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP280234
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