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IGF1R and MAPK15 Emerge as Potential Targets of Pentabromobenzylisothioureas in Lung Neuroendocrine Neoplasms

Pentabromobenzylisothioureas are antitumor agents with diverse properties, including the inhibition of MAPK15, IGF1R and PKD1 kinases. Their dysregulation has been implicated in the pathogenesis of several cancers, including bronchopulmonary neuroendocrine neoplasms (BP-NEN). The present study asses...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Motylewska, Ewelina, Braun, Marcin, Kazimierczuk, Zygmunt, Ławnicka, Hanna, Stępień, Henryk
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692632/
https://ncbi.nlm.nih.gov/pubmed/33138224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13110354
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