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Chain-Selective Isotopic Labeling of the Heterodimeric Type III Secretion Chaperone, Scc4:Scc1, Reveals the Total Structural Rearrangement of the Chlamydia trachomatis Bi-Functional Protein, Scc4

Scc4 is an unusual bi-functional protein from Chlamydia trachomatis (CT) that functions as a type III secretion system (T3SS) chaperone and an RNA polymerase (RNAP)-binding protein. Both functions require interactions with protein partners during specific stages of the CT developmental cycle. As a T...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Ukwaththage, Thilini O., Keane, Samantha M., Shen, Li, Macnaughtan, Megan A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692554/
https://ncbi.nlm.nih.gov/pubmed/33114427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10111480
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