Antitumour Activity of the Ribonuclease Binase from Bacillus pumilus in the RLS(40) Tumour Model Is Associated with the Reorganisation of the miRNA Network and Reversion of Cancer-Related Cascades to Normal Functioning

The important role of miRNA in cell proliferation and differentiation has raised interest in exogenous ribonucleases (RNases) as tools to control tumour-associated intracellular and extracellular miRNAs. In this work, we evaluated the effects of the RNase binase from Bacillus pumilus on small non-co...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Mohamed, Islam Saber Ead, Sen’kova, Aleksandra V., Nadyrova, Alsu I., Savin, Innokenty A., Markov, Andrey V., Mitkevich, Vladimir A., Makarov, Aleksander A., Ilinskaya, Olga N., Mironova, Nadezhda L., Zenkova, Marina A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692507/
https://ncbi.nlm.nih.gov/pubmed/33147876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10111509
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